D0629

3,5-Diiodo-L-thyronine

thyroid hormone analog

• Synonym(s): 3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine, 3,5-T2, O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
• Empirical Formula (Hill Notation): C₁₅H₁₃I₂NO₄
• CAS Number: 1041-01-6
• Molecular Weight: 525.08
• UNSPSC Code: 41116107
• NACRES: NA.26
• PubChem Substance ID: 24893248
• EC Number: 213-867-7
• Beilstein/REAXYS Number: 2707891
• MDL number: MFCD00064987

Properties

• Quality Segment: 200
• assay: ≥99% (HPLC)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white to off-white
• mp: 255 °C
• storage temp.: −20°C
• SMILES string: N[C@@H](Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(O)=O
• InChI: 1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1
• InChI key: ZHSOTLOTTDYIIK-ZDUSSCGKSA-N

Description

Biochem/physiol Actions

3,5-Diiodo-L-thyronine ((T(2)) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.

Safety Information

• hcodes: H412
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves