Key Documents

View All Documentation

Cimetidine

Name: Cimetidine
Brand: SIGMA

histamine H2 receptor antagonist, powder

Synonym(s):

SKF-92334

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₆N₆S

CAS Number:

51481-61-9

Molecular Weight:

252.34

NACRES:

NA.77

PubChem Substance ID:

24277766

UNSPSC Code:

12352200

EC Number:

257-232-2

MDL number:

MFCD00133296

Form:

powder

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Cimetidine,

form

powder

Quality Segment

200

originator

GlaxoSmithKline

storage temp.

2-8°C

SMILES string

CN\C(NC#N)=N\CCSCc1nc[nH]c1C

InChI

1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)

InChI key

AQIXAKUUQRKLND-UHFFFAOYSA-N

Gene Information

human ... ABCB1(5243), CYP1A2(1544), CYP3A4(1576), HRH2(3274), SLC9A2(6549), SLC9A5(6553)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Slc9a1(24782), Slc9a3(24784), Slc9a5(192215)

Description

Biochem/physiol Actions

H₂ histamine receptor antagonist; I₁ imidazoline receptor agonist; anti-ulcer agent. Blocks cancer metastasis by inhibiting the expression of E-selectin on the surface of endothelial cells, thus blocking tumor cell adhesion.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	C2175000	Y0001130	E2535
Sigma-Aldrich C4522 Cimetidine	C2175000 Cimetidine	Y0001130 Cimetidine for peak identification	Sigma-Aldrich E2535 Eprosartan mesylate
description -	description European Pharmacopoeia (EP) Reference Standard	description European Pharmacopoeia (EP) Reference Standard	description ≥98% (HPLC)
form powder	form -	form -	form powder
Quality Level 200	Quality Level -	Quality Level -	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. room temp
originator GlaxoSmithKline	originator -	originator -	originator Abbott
Gene Information human ... ABCB1(5243), CYP1A2(1544), CYP3A4(1576), HRH2(3274), SLC9A2(6549), SLC9A5(6553) mouse ... Abcb1a(18671), Abcb1b(18669) rat ... Slc9a1(24782), Slc9a3(24784), Slc9a5(192215)	Gene Information human ... HRH2(3274)	Gene Information human ... HRH2(3274)	Gene Information human ... AGTR1(185)

Still not finding the right product?

Explore all of our products under Cimetidine

Storage Class

11 - Combustible Solids

WGK

WGK 3

PPE (personal protective equipment)

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.