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Alcian Blue 8GX

Name: Alcian Blue 8GX
Brand: SIGMA

BioReagent, suitable for detection of glycoproteins

Synonym(s):

Alcian Blue, Ingrain Blue 1

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About This Item

Empirical Formula (Hill Notation):

C₅₆H₆₈Cl₄CuN₁₆S₄

CAS Number:

33864-99-2

Molecular Weight:

1298.86

UNSPSC Code:

12171500

NACRES:

NA.32

PubChem Substance ID:

24891421

EC Number:

251-705-7

Colour Index Number:

74240

MDL number:

MFCD00010720

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Properties

product line

BioReagent

Quality Segment

100

form

powder

composition

Dye content, ~50%

technique(s)

electrophoresis: suitable

suitability

suitable for detection of glycoproteins

SMILES string

[Cl-].[Cl-].[Cl-].[Cl-].CN(C)C(\SCc1ccc2c3nc(nc4n5[Cu]n6c(nc7nc(nc5c8cc(CS\C(N(C)C)=[N+](\C)C)ccc48)c9ccc(CS\C(N(C)C)=[N+](\C)C)cc79)c%10ccc(CS\C(N(C)C)=[N+](\C)C)cc%10c6n3)c2c1)=[N+](/C)C

InChI

1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4

InChI key

CKLBXIYTBHXJEH-UHFFFAOYSA-J

Description

General description

Alcian Blue 8GX is a cationic[1] phthalocyanine dye.[2] It has an ability to interact with sulphated glycosaminoglycan.[1] It is used as a counterstain to visualize histological tissue sections. In addition, alcian blue 8GX also aids in the in-situ quantification of marine biofilms produced by marine bacteria.[2]

Application

Alcian Blue 8GX has been used:

for the quantification of sulphated glycosaminoglycan[1]
to stain differentiated chondrocytes to access proteoglycan′s synthesis by these cells[3][4]
to stain Multi-lineage differentiation of hemangioma-derived perivascular cells (Hem-PCs)[4]
in histological staining to detect neutral and charged carbohydrate residues[5]

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This Item	A3157	A5268	05500
Sigma-Aldrich A9186 Alcian Blue 8GX	Sigma-Aldrich A3157 Alcian Blue 8GX	Sigma-Aldrich A5268 Alcian Blue 8GX	Sigma-Aldrich 05500 Alcian Blue 8GX
technique(s) electrophoresis: suitable	technique(s) microbe id \| staining: suitable	technique(s) microbe id \| staining: suitable	technique(s) -
suitability suitable for detection of glycoproteins	suitability -	suitability -	suitability -
form powder	form powder or crystals	form powder	form powder
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
composition Dye content, ~50%	composition Dye content, ≥50%	composition Dye content, 45-65%	composition -
product line BioReagent	product line -	product line -	product line -

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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