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Sigma-Aldrich

Naphthol AS-MX Phosphate Alkaline Solution, 0.25%

Synonym(s):

Naphthol AS-MX phosphate

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About This Item

Empirical Formula (Hill Notation):
C19H18NO5P
CAS Number:
1596-56-1
Molecular Weight:
371.32
Beilstein:
6664873
EC Number:
216-480-1
MDL number:
MFCD00042711
UNSPSC Code:
12352204
PubChem Substance ID:
24888366
NACRES:
NA.47

form

solution

Quality Level

500

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

concentration

0.25 % (w/v)

pH

8.6

application(s)

hematology
histology

storage temp.

2-8°C

SMILES string

Cc1ccc(NC(=O)c2cc3ccccc3cc2OP(O)(O)=O)c(C)c1

InChI

1S/C19H18NO5P/c1-12-7-8-17(13(2)9-12)20-19(21)16-10-14-5-3-4-6-15(14)11-18(16)25-26(22,23)24/h3-11H,1-2H3,(H,20,21)(H2,22,23,24)

InChI key

IOMLBTHPCVDRHM-UHFFFAOYSA-N

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Application

For use in Sigma Procedure 85 (kit numbers 85L1 and 85L2) for the demonstration of Alkaline Phosphatase, Leukocyte (LAP).
Substrate for the histochemical demonstration of alkaline phosphatase.

Components

Naphthol AS-MX phosphate, 0.25% (w/v), buffered at pH 8.6, 25 C

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gianluca Cidonio et al.
Biofabrication, 12(3), 035010-035010 (2020-04-08)
Acellular soft hydrogels are not ideal for hard tissue engineering given their poor mechanical stability, however, in combination with cellular components offer significant promise for tissue regeneration. Indeed, nanocomposite bioinks provide an attractive platform to deliver human bone marrow stromal
J Espada et al.
Histochemistry and cell biology, 108(6), 481-487 (1998-02-05)
The aim of this work was the development of a fluorescent microscopy technique to visualize acid phosphatase activity in living and pre-fixed cells. We have shown that a coupling azo dye method, using naphthol AS-MX phosphate (NP) as substrate and
N C Talbot et al.
Molecular reproduction and development, 36(2), 139-147 (1993-10-01)
To define better the characteristics of pig and sheep epiblast cells in culture, the cells were tested for the presence of alkaline phosphatase (AP), a biochemical marker characteristic of mouse embryonic stem cells. Pig and sheep epiblast cells were positive
Lei Shu et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 26(5), 1057-1071 (2011-05-05)
We have investigated, in neonates, whether the calcium-sensing receptor (CaR) mediates the effects of dietary calcium on bone turnover and/or modulates parathyroid hormone (PTH)-induced bone turnover. Wild-type (WT) pups and pups with targeted deletion of the Pth (Pth(-/-)) gene or
Yongxin Ren et al.
PloS one, 6(7), e23060-e23060 (2011-08-11)
Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited. Furthermore it is unknown whether
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