49409

Phalloidin-Atto 488

BioReagent, suitable for fluorescence, ≥90% (HPLC)

• Synonym(s): Atto 488, Atto 488 Phalloidin
• NACRES: NA.25
• UNSPSC Code: 12161900

Properties

• product line: BioReagent
• Quality Segment: 100
• assay: ≥90% (HPLC)
• form: solid
• manufacturer/tradename: ATTO-TEC GmbH
• concentration: ≤100% (Atto 488 Phalloidin)
• color: orange
• λmax: 499-505 nm in water
• λ: in water
• UV absorption: λ: 499-505 nm A_max
• suitability: suitable for fluorescence
• storage temp.: −20°C

Description

General description

Phalloidin Atto 488is a hydrophilic fluorescent label with high water solubility. Post coupling to a substrate, the fluorescent label carries a net electrical charge of -1. The fluorescence activity is excited efficiently at the 480-515nm range. A suitable excitation source for Phalloidin Atto 488 is the 488 nm line of the Argon-Ion laser.

Application

Phalloidin Atto 488 is used for labeling F-actin in fixed cells since the binding nature is like natural phallacidin. Phalloidin conjugates identify and quantify F-actin in tissues, cell cultures, or cell-free preparations. Since fluorescent Phalloidin Atto 488 conjugates are non-permeable to live cells, it is suitable to identify cells with compromised membranes.

Features and Benefits

Characteristic features of the Phalloidin Atto 488 are:

• Strong Absorption.
• High Fluorescence quantum yield.
• High Photostability.
• Minimal Triplet formation.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges