28605

3-Cyanoumbelliferone

BioReagent, suitable for fluorescence, ≥98.0% (TLC)

• Synonym(s): 3-Cyano-7-hydroxycoumarin
• Empirical Formula (Hill Notation): C₁₀H₅NO₃
• CAS Number: 19088-73-4
• Molecular Weight: 187.15
• UNSPSC Code: 12352108
• NACRES: NA.32
• PubChem Substance ID: 57648313
• MDL number: MFCD00037480
• Beilstein/REAXYS Number: 153271

Properties

• product line: BioReagent
• Quality Segment: 100
• assay: ≥98.0% (TLC)
• form: powder
• solubility: DMF: soluble, alcohols: soluble
• fluorescence: λ_ex 408 nm; λ_em 450 nm in methanol
• suitability: suitable for fluorescence
• SMILES string: Oc1ccc2C=C(C#N)C(=O)Oc2c1
• InChI: 1S/C10H5NO3/c11-5-7-3-6-1-2-8(12)4-9(6)14-10(7)13/h1-4,12H
• InChI key: IJQYTHQDUDCJEQ-UHFFFAOYSA-N
• Gene Information: human ... MIF(4282)

Description

Application

3-Cyano-7-hydroxycoumarin is closely related to 3-cyano-7-ethoxycoumarin which is used as a fluorometric substrate and inhibitor for cytochrome P-450 enzymes and cytochrome P-450-dependent mixed function oxidases. 3-Cyano-7-hydroxycoumarin may be useful to study the kinetics and substrate specificity of cytochrome P-450s.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves