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Merck

ED2P

Ethylenediaminetetraacetic acid dipotassium salt dihydrate

≥98%

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid dipotassium salt, Dipotassium ethylenediaminetetraacetate dihydrate, EDTA dipotassium salt, Edathamil, Potassium ethylenediaminetetraacetate dibasic

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About This Item

Linear Formula:
HOOCCH2(KOOCCH2)NCH2CH2N(CH2COOK)CH2COOH · 2H2O
CAS Number:
Molecular Weight:
404.45
NACRES:
NA.77
UNSPSC Code:
12352107
EC Number:
217-895-0
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biological source

synthetic

Quality Level

assay

≥98%

form

powder

reaction suitability

reagent type: chelator

pH

4.0-5.0 (25 °C, 40.4 g/L)

mp

255-280 °C (dec.) (lit.)

solubility

3 M KOH: 160 mg/mL, clear to very slightly hazy, colorless to faintly yellow

storage temp.

room temp

SMILES string

O.O.O.O.[K+].[K+].[K+].[K+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2K.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

JFROQFOCFOKDKU-UHFFFAOYSA-L

Application

Used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals
Ethylenediaminetetraacetic acid dipotassium salt dehydrate has been used as a component:
  • of EDTA–glycerol solution (EDTA-G) for decalcification
  • of buffer for monoamine and pterine analysis
  • of T-cell resuspension buffer

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium disodium EDTA administration is effective in slowing down the progression of chronic kidney disease. It also enhances the antimicrobial functionality of lysozyme and improves shelf life of cheese.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Inhalation

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves



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A novel decalcification method for adult rodent bone for histological analysis of peripheral-central nervous system connections
Begum F, et al.
Journal of Neuroscience Methods, 187(1), 59-66 (2010)
Cytochrome c oxidase activity is a metabolic checkpoint that regulates cell fate decisions during T cell activation and differentiation
Tarasenko TN, et al.
Cell Metabolism, 25(6), 1254-1268 (2017)
Whole body insulin responsiveness is higher in beef steers selected for increased muscling
McGilchrist P, et al.
Animal : An International Journal of Animal Bioscience, 5(10), 1579-1586 (2011)



Global Trade Item Number

SKUGTIN
ED2P-1KG04061835544769
ED2P-500G04061835544776
ED2P-100G04061835544752