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Sodium salicylate

Name: Sodium salicylate
Brand: SIAL

99.5-101.0% (calc. to the dried substance), puriss. p.a., reag. Ph. Eur.

Synonym(s):

2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

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About This Item

Linear Formula:

HOC₆H₄COONa

CAS Number:

54-21-7

Molecular Weight:

160.10

NACRES:

NA.21

PubChem Substance ID:

57648580

UNSPSC Code:

12352100

EC Number:

200-198-0

MDL number:

MFCD00002440

Beilstein/REAXYS Number:

3732792

Assay:

99.5-101.0% (calc. to the dried substance)

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Properties

Product Name

Sodium salicylate, puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Quality Segment

100

agency

USP/NF, reag. Ph. Eur.

grade

puriss. p.a.

assay

99.5-101.0% (calc. to the dried substance)

impurities

acidic reac. impurities, complies, sulfite or thiosulfate, complies, ≤0.001% heavy metals (as Pb)

loss

≤0.3% loss on drying, 105 °C

mp

>300 °C (lit.)

anion traces

chloride (Cl^-): ≤20 mg/kg, sulfate (SO₄^2-): ≤500 mg/kg

cation traces

Fe: ≤10 mg/kg

suitability

in accordance for appearance of solution

SMILES string

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

InChI key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

Description

General description

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.

Application

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia. It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from mixed micelles.

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This Item	567630	PHR3238	S0800000
Sigma-Aldrich 31493 Sodium salicylate	Sigma-Aldrich 567630 Sodium Salicylate	Supelco PHR3238 Sodium Salicylate	S0800000 Sodium salicylate
description puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)	description A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein.	description pharmaceutical secondary standard, certified reference material	description European Pharmacopoeia (EP) Reference Standard
assay 99.5-101.0% (calc. to the dried substance)	assay ≥98% (titration)	assay -	assay -
Quality Level 100	Quality Level 100	Quality Level 300	Quality Level -
grade puriss. p.a.	grade -	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard
impurities sulfite or thiosulfate, complies, ≤0.001% heavy metals (as Pb), acidic reac. impurities, complies	impurities -	impurities -	impurities -
mp >300 °C (lit.)	mp -	mp >300 °C (lit.)	mp >300 °C (lit.)
cation traces Fe: ≤10 mg/kg	cation traces -	cation traces -	cation traces -

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Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Codes

H302,H319,H361d

Precautionary Statements

P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

208.9 °F - Pensky-Martens closed cup

Flash Point (°C)

98.3 °C - Pensky-Martens closed cup

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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