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18493

Millipore

MUG Supplement

suitable for microbiology

Synonym(s):

4-Methylumbelliferyl-β-D-glucuronide, 4-Methylumbelliferyl-β-D-glucuronide Supplement, MUGlcU

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About This Item

Empirical Formula (Hill Notation):
C16H16O9
CAS Number:
Molecular Weight:
352.29
EC Number:
MDL number:
UNSPSC Code:
41171614
PubChem Substance ID:
NACRES:
NA.85

sterility

sterile

Quality Level

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental
food and beverages

microbiology

storage temp.

2-8°C

suitability

Escherichia coli
coliforms

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C(O)=O)O[C@H]1OC2=CC(OC(C=C3C)=O)=C3C=C2

InChI

1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key

ARQXEQLMMNGFDU-JHZZJYKESA-N

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Application

Fluorogenic substrate for measuring of ß-glucoronidiase activity, for identifiacation of Escherichia coli.

Components

(per vial, sufficient for 500 ml medium)
4-Methylumbelliferyl ß-D-glucuronide (MUG) 50.0 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Garcia-Armisen et al.
Letters in applied microbiology, 40(4), 278-282 (2005-03-09)
The relationships between the beta-D-glucuronidase (GLUase) activity, the abundance of culturable Escherichia coli and the number of viable E. coli were investigated in river and wastewater samples. GLUase activity was measured as the rate of hydrolysis of 4-methylumbelliferyl-beta-D-glucuronide. Culturable E.
Bernhard Sperker et al.
Life sciences, 71(13), 1547-1557 (2002-07-20)
Antibody directed enzyme prodrug therapy (ADEPT) using glucuronide prodrugs is an experimental approach to reduce systemic toxicity of anti-cancer agents. Bioactivation of such prodrugs is achieved by fusion proteins consisting of targeting moieties (e.g. ligands of tumor specific antigens) and
Michael B Tropak et al.
The Journal of biological chemistry, 279(14), 13478-13487 (2004-01-16)
Tay-Sachs and Sandhoff diseases are lysosomal storage disorders that result from an inherited deficiency of beta-hexosaminidase A (alphabeta). Whereas the acute forms are associated with a total absence of hexosaminidase A and early death, the chronic adult forms exist with
Adrian Unc et al.
Applied and environmental microbiology, 72(3), 2287-2289 (2006-03-07)
Laboratory batch tests indicate that addition of sterile municipal sewage biosolids to clay soil from four depths increases the numbers of Escherichia coli isolates recoverable in EC-MUG broth (EC broth with 4-methylumbelliferyl-beta-glucuronide). This effect was most marked for the deeper
Si-Cheng Liang et al.
Journal of pharmaceutical and biomedical analysis, 54(1), 236-241 (2010-09-11)
Propofol O-glucuronidation has been used as probe reaction to phenotype UGT1A9 activity in human liver, thus a sensitive and specific method for determination of propofol O-glucuronide (PG) is urgently desirable. In the current study, a new LC-ESI-MS method for determination

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