8.55047

NovaPEG Rink Amide resin

Novabiochem^®

• UNSPSC Code: 12352111
• eCl@ss: 32150917

Properties

• Quality Segment: 200
• product line: NovaPEG, Novabiochem^®
• form: beads
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: amine
• storage temp.: 2-8°C

Description

General description

An excellent acid-labile resin for the continuous flow and batch Fmoc SPPS of peptide amides. This resin is prepared by derivatization of NovaPEG amino resin with the modified Rink linker. The support has excellent swelling properties in a wide range of solvents, including water, MeCN, MeOH, DCM, DMF, THF, and toluene. In comparative studies this resin was found to give better results than polystyrene-based supports in the synthesis of hydrophobic peptides. The high hydrophilicity was also found to benefit on-resin immunoassays with one-bead-one-peptide libraries ^[1].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Analysis Note

Colour (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.60 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
PEG based resin; 35 - 100 mesh

Other Notes

Replaces: 01-64-0473

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable