8.55028
FMPB AM resin
Novabiochem®
Synonym(s):
4-(4-Formyl-3-methoxyphenoxy)butyryl AM resin
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About This Item
Quality Level
product line
Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
aldehyde
storage temp.
2-30°C
General description
This support is an excellent tool for the production of C-terminal secondary amides. Primary amines can be loaded onto the resin by reductive amination. Following standard Fmoc SPPS, treatment with TFA releases the peptide secondary amides.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Application
- Structural and functional cell and organelle mimics: Utilizes FMPB AM resin in the solid-phase peptide synthesis for specific functionalities in cell and organelle mimics, detailing the chemical modification processes involved. (RJRW Peters, 2015).
Linkage
Replaces: 01-64-0209
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide): 0.80 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh
Appearance of substance (visual): beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide): 0.80 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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