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8.52354

Sigma-Aldrich

Fmoc-N-Me-His(Trt)-OH

Novabiochem®

Synonym(s):

Fmoc-N-Me-His(Trt)-OH, N-α-Fmoc-N-α-methyl-im-trityl-L-histidine

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About This Item

Empirical Formula (Hill Notation):
C41H35N3O4
CAS Number:
1217840-61-3
Molecular Weight:
633.73
MDL number:
MFCD04974256
UNSPSC Code:
12352200

product line

Novabiochem®

Assay

≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

shipped in

ambient

storage temp.

15-25°C

General description

Building block for introduction of N-α-methyl-histidine amino-acid residues by Fmoc SPPS. Product has poor solubility but does dissolve upon activation in NMP with HBTU/DIPEA.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 97.0 % (a/a)

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

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Unnatural Amino Acids for Peptide Synthesis

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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