Skip to Content
Merck
All Photos(1)

Documents

454582

Sigma-Aldrich

Anti-NMDAR 2B (984-1104) Rabbit pAb

lyophilized, Calbiochem®

Synonym(s):

Anti-N-Methyl-D-Aspartate Receptor 2B-Subunit

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized

does not contain

preservative

species reactivity

rat, fish, mouse, human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

isotype

IgG

shipped in

ambient

storage temp.

−20°C

target post-translational modification

unmodified

General description

Immunoaffinty purified rabbit polyclonal antibody. Recognizes the ~180 kDa NMDAR2B subunit of the NMDA receptor.
Recognizes the ~180 kDa NMDA receptor NR2B subunit.
This Anti-NMDAR 2B (984-1104) Rabbit pAb is validated for use in Immunoblotting, Immunohistochemistry, Immunoprecipitation for the detection of NMDAR 2B (984-1104).

Immunogen

Rat Brain
a recombinant fusion protein consisting of amino acids 984-1104 of rat brain NMDAR 2B-subunit

Application

Immunoblotting (1:1000)

Immunohistochemistry (1:1000-1:2000)

Immunoprecipitation (see comments)

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 5 mM ammonium bicarbonate.

Reconstitution

Reconstitute in 50 µl PBS. Following reconstitution, aliquot and freeze (-20°C). Avoid freeze thaw cycles of reconstituted solution.

Other Notes

Does not cross-react with NMDAR2A or NMDAR2C. Please refer to the certificate of analysis for lot-specific immunoprecipitation volume. Variables associated with assay conditions will dictate the proper working dilution.
Wang, Y.H., et al. 1995. J. Neurochem.65, 176.
Petralia, R.S., et al. 1994. J. Neurosci.14, 6102.
Ishii, T., et al. 1993. J. Biol. Chem.268, 2836.
Monyer, H., et al. 1992. Nature256, 1217.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ainhoa Plaza-Zabala et al.
Neuroscience letters, 557 Pt B, 101-106 (2013-11-23)
Hypocretin peptides are critical for the effects of cocaine on excitatory synaptic strength in the ventral tegmental area (VTA). However, little is known about their role in cocaine-induced synaptic plasticity in the nucleus accumbens (NAc). First, we tested whether hypocretin-1
Carrie R Ferrario et al.
PloS one, 7(8), e40898-e40898 (2012-08-08)
We previously showed that the time-dependent intensification ("incubation") of cue-induced cocaine seeking after withdrawal from extended-access cocaine self-administration is accompanied by accumulation of Ca(2+)-permeable AMPA receptors (CP-AMPARs) in the rat nucleus accumbens (NAc). These results suggest an enduring change in
Daniela Bonini et al.
Neural plasticity, 2016, 7267865-7267865 (2016-03-12)
Clinical studies on patients with stress-related neuropsychiatric disorders reported functional and morphological changes in brain areas where glutamatergic transmission is predominant, including frontal and prefrontal areas. In line with this evidence, several preclinical works suggest that glutamate receptors are targets
Leonardo Santana Novaes et al.
Translational psychiatry, 11(1), 18-18 (2021-01-09)
The persistence of anxiety and the deficit of fear memory extinction are both phenomena related to the symptoms of a trauma-related disorder, such as post-traumatic stress disorder (PTSD). Recently we have shown that single acute restraint stress (2 h) in rats
Carrie R Ferrario et al.
Neuroscience letters, 490(3), 180-184 (2010-12-25)
We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service