437692

α-Lipoic Acid

α-Lipoic Acid, CAS 1077-28-7 is an oxidized form with antioxidant properties. Reduces renal lipid peroxidation in rats with cisplatin n-induced nephrotoxicity.

• Synonym(s): α-Lipoic Acid, DL-Thioctic Acid
• Empirical Formula (Hill Notation): C₈H₁₄O₂S₂
• CAS Number: 1077-28-7
• Molecular Weight: 206.33
• MDL number: MFCD00005474
• UNSPSC Code: 12352106
• NACRES: NA.77

Properties

• Quality Level: 100
• description: Merck USA index - 14, 9326
• Assay: ≥99% (by assay)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: pale yellow
• solubility: ethanol: soluble; methanol: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: S1SCCC1CCCCC(=O)O
• InChI: 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
• InChI key: AGBQKNBQESQNJD-UHFFFAOYSA-N

Description

General description

Oxidized form. Has antioxidant properties. Growth factor for many bacteria and protozoa.

Oxidized form. Has antioxidant properties. Reported to effectively reduce renal lipid peroxidation in rats with cisplatin-induced nephrotoxicity. Acts as a growth factor for many bacteria and protozoa.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Reduce renal lipid peroxidation in rats with cisplatin-induced nephrotoxicity

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Harmful (C)

Other Notes

Somami, S. M., et al. 2000. Pharmacol. Toxicol. 86, 234.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H317,H319,H411
• Precautionary Statements: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable