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671401

Sigma-Aldrich

N-Boc-N′-succinyl-4,7,10-trioxa-1,13-tridecanediamine

95% (HPLC)

Synonym(s):

17-Oxo-6,9,12-trioxa-2,16-diazaeicosanedioic acid 1-(1,1-dimethylethyl)ester

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About This Item

Empirical Formula (Hill Notation):
C19H36N2O8
CAS Number:
250612-31-8
Molecular Weight:
420.50
MDL number:
MFCD10566970
UNSPSC Code:
12352116
PubChem Substance ID:
329760420
NACRES:
NA.22

Assay

95% (HPLC)

reaction suitability

reagent type: cross-linking reagent

functional group

Fmoc
amine
carboxylic acid

storage temp.

−20°C

SMILES string

O=C(CCC(O)=O)NCCCOCCOCCOCCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O

InChI

1S/C19H36N2O8/c1-19(2,3)29-18(25)21-9-5-11-27-13-15-28-14-12-26-10-4-8-20-16(22)6-7-17(23)24/h4-15H2,1-3H3,(H,20,22)(H,21,25)(H,23,24)

InChI key

RTHQDNQOODHVLK-UHFFFAOYSA-N

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Maria Davydova et al.
Journal of visualized experiments : JoVE, (145) (2019-03-26)
Maleimide-bearing bifunctional probes have been employed for decades for the site-selective modification of thiols in biomolecules, especially antibodies. Yet maleimide-based conjugates display limited stability in vivo because the succinimidyl thioether linkage can undergo a retro-Michael reaction. This, of course, can

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