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SRP5144

Sigma-Aldrich

Stathmin, His tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

C1orf215, FLJ32206, LAP18, Lag, MGC138869, MGC138870, OP18, PP17, PP19, PR22, SMN, STMN1

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About This Item

CAS Number:
956166-50-0
UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

~19 kDa

NCBI accession no.

BC014353

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... STMN1(3925)

Physical form

Supplied in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Covalent modification of stathmin by CCNU determined by FTMS analysis of modified proteins and tryptic peptides.
Wu WW
Biochemical and Biophysical Research Communications, 367(1), 7-13 (2008)
STMN1 overexpression correlates with biological behavior in human cutaneous squamous cell carcinoma.
Li X
Pathology Research and Practice, 211(11), 816-823 (2015)
The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network.
Gavet O
Journal of Cell Science, 111(Pt 22), 3333-3346 (1998)
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro.
Velasco, et al.
Communications biology, 6, 488-488 (2023)
A Sobel
Trends in biochemical sciences, 16(8), 301-305 (1991-08-01)
Stathmin is a ubiquitous, phylogenetically conserved protein present in the cytoplasm of cells in a variety of unphosphorylated and phosphorylated forms. Its expression and phosphorylation are regulated throughout development and in response to extracellular signals regulating cell proliferation, differentiation and
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