Skip to Content
Merck
All Photos(1)

Key Documents

SRP2027

Sigma-Aldrich

E2F-1 (RBAP-1) human

recombinant, expressed in insect cells, ≥70% (SDS-PAGE)

Synonym(s):

E2F-1, RBAP1, RBBP3, RBP3

Sign Into View Organizational & Contract Pricing

Select a Size

5 μG
£559.00

£559.00

Please contact Customer Service for Availability
All Photos(1)

Select a Size

Change View
5 μG
£559.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.26

£559.00

Please contact Customer Service for Availability

biological source

human

recombinant

expressed in insect cells

Assay

≥70% (SDS-PAGE)

form

frozen liquid

mol wt

~48.6 kDa

packaging

pkg of 5 μg

concentration

400 μg/mL

color

colorless to clear

NCBI accession no.

NM_005225

UniProt accession no.

Q01094

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... E2F1(189971)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SRP2081SRP2156SRP2033
E2F-1 (RBAP-1) human recombinant, expressed in insect cells, ≥70% (SDS-PAGE)

SRP2027

E2F-1 (RBAP-1) human

Retinoblastoma protein human recombinant, expressed in insect cells, ≥70% (SDS-PAGE)

SRP2081

Retinoblastoma protein human

STAT1 human recombinant, expressed in insect cells, ≥70% (SDS-PAGE)

SRP2156

STAT1 human

Topo I (197-651) (core domain) human recombinant, expressed in insect cells, ≥80% (SDS-PAGE)

SRP2033

Topo I (197-651) (core domain) human

biological source

human

biological source

human

biological source

human

biological source

human

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥80% (SDS-PAGE)

concentration

400 μg/mL

concentration

400 μg/mL

concentration

600 μg/mL

concentration

500 μg/mL

form

frozen liquid

form

frozen liquid

form

frozen liquid

form

frozen liquid

Gene Information

human ... E2F1(189971)

Gene Information

human ... RB1(5925)

Gene Information

human ... STAT1(6772)

Gene Information

human ... TOP1(7150)

Biochem/physiol Actions

E2F was originally identified as a transcription factor mediating the transcription of adenovirus E2 gene. It is a heterodimer composed of two structurally related subunits, termed E2F and DP. E2F is encoded by at least five genes, E2F-1 through E2F-5, and DP is encoded by at least two genes, DP-1 and DP-2. All these genes (E2F-1 through E2F-5, DP-1 and DP-2) have been considered as members of the E2F gene family because they have a number of common structural and functional characteristics. Among those members of the E2F family, E2F-1 was the first E2F gene cloned and characterized. The E2F-1 protein has been shown to interact with RB both in vitro and in vivo. Although the E2F proteins can function as transcription factors by themselves, they should be considered as RB-mediators as well because almost every functional response of RB protein(s) requires the presence of E2F protein(s).

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
055103021

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S Bagchi et al.
Cell, 62(4), 659-669 (1990-08-24)
Adenovirus infection activates the E2F transcription factor, in part through the formation of a heteromeric protein complex involving a 19 kd E4 gene product that then allows cooperative and stable promoter binding. We now find that cellular factors are complexed
K Helin et al.
Cell, 70(2), 337-350 (1992-07-24)
The retinoblastoma protein (pRB) plays an important role in the control of cell proliferation, apparently by binding to and regulating cellular transcription factors such as E2F. Here we describe the characterization of a cDNA clone that encodes a protein with
W G Kaelin et al.
Cell, 70(2), 351-364 (1992-08-03)
An expression vector was modified to permit the rapid synthesis of purified, 32P-labeled, glutathione S-transferase (GST)-retinoblastoma (RB) fusion proteins. The products were used to screen lambda gt11 expression libraries, from which we cloned a cDNA encoding a polypeptide (RBAP-1) capable

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service