Synthetic 17 amino acid peptide from 2nd extracellular domain of human RXFP2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Elephant, Panda, Bat, Horse (94%); Monkey, Dog, Pig (88%); Bovine, Rabbit, Platypus, Xenopus (82%).
Biochem/physiol Actions
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). LGR8 is a member of the Relaxin Receptor subfamily. LGR8 has been shown to be important for testis descent.
Features and Benefits
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Physical form
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.
Supplied at 1 mg/ml
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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