As reported in the 'DESCRIPTION' section of the product page, Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. This product has not been further characterized.
S1006
Sulfatides from bovine brain
≥97% (TLC), powder
Synonym(s):
Cerebroside sulfate
Sign Into View Organizational & Contract Pricing
Select a Size
5 MG
£231.00
10 MG
£601.00
50 MG
£1,630.00
£231.00
List Price£330.00Save 30%Please contact Customer Service for Availability
Request a Bulk Order
All Photos(2)
Select a Size
Change View
5 MG
£231.00
10 MG
£601.00
50 MG
£1,630.00
About This Item
UNSPSC Code:
12352200
NACRES:
NA.77
£231.00
List Price£330.00Save 30%Please contact Customer Service for Availability
Request a Bulk Order
Recommended Products
General description
Sulfatideis a glycospingolipid and plays an essential role in host-pathogen recognition,β-cell function, infection, haemostasis/thrombosis, protein trafficking, cellgrowth, cell adhesion, neuronal plasticity, cell morphogenesis, and signaltransduction.[1][2] It is found on the surface of the blood cells such asplatelets, leukocytes, and erythrocytes. Sulfatides are also found in the serumas glycosphingolipids in lipoproteins.[3] It is made up of glycan part, a hydrophobic part, 3-O-sulfated galactose, and ceramide, which in turn is composed of a sphingosine base and a fatty acid.[1] It is an important component forthe maintenance of the myelin sheath andproper formation of the axo-glial junctions. Variations in the production ofsulfatides are associated with various human diseases like cancer andimmunological disorders. Alterations in the sulfatide metabolism lead to synapticdysfunction, neurological decline, inflammation, and myelin deterioration.[1]
Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. It is localized in myelin sheath and comprises approximately 4% of total myelin lipid in brain.[4]
Application
Biochem/physiol Actions
Sulfatides play a key role in physiological processes of nervous system, immune system and in insulin secretion.[4] Anomalies in sulfatides catabolism in lysosome is implicated in late infantile metachromatic leukodystrophy.[8] High levels of sulfatides is also observed in ovarian cancer.[9] Sulfatides contribute to the pathogenesis of chronic inflammatory diseases of the central nervous system.[10]
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway
Kouser L, et al.
Molecular Immunology, 73(11), 76-87 (2016)
C Mazurier et al.
Bailliere's clinical haematology, 9(2), 229-241 (1996-06-01)
von Willebrand disease (vWD), the most common congenital bleeding disorder in man, is related to quantitative and/or qualitative abnormalities of von Willebrand factor (vWF), a protein necessary for platelet-vessel wall interactions and for carrying factor VIII. Distinct abnormalities of vWF
Mamoru Kyogashima
Archives of biochemistry and biophysics, 426(2), 157-162 (2004-05-26)
In 1961, Wago et al. reported a potential anticoagulant role for sulfatide using animal experiments. Since then there have been many studies of sulfatide in the field of thrombogenesis/haemostasis, yielding contradictory conclusions. Some report that sulfatide has anti-thrombotic activity because
Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry
Liu Y, et al.
Molecular Cancer, 9(1), 186-186 (2010)
Quantification of sulfatides and lysosulfatides in tissues and body fluids by liquid chromatography tandem mass spectrometry
Mirzaian M, et al.
Journal of Lipid Research, 56(8), 936-943 (2015)
Articles
Discover Bioactive Small Molecules for Lipid Signaling Research
-
Hi, Do you have any information about the sulfatide composition/profile of “Sulfatide from bovine brain (S1006)”.
1 answer-
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
