G7379
Guanidinosuccinic acid
Synonym(s):
N-Amidino-L-aspartic acid
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About This Item
Linear Formula:
C5H9O4N3
CAS Number:
Molecular Weight:
175.14
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Pricing and availability is not currently available.
form
powder
color
white
storage temp.
2-8°C
SMILES string
NC(=N)NC(CC(O)=O)C(O)=O
InChI
1S/C5H9N3O4/c6-5(7)8-2(4(11)12)1-3(9)10/h2H,1H2,(H,9,10)(H,11,12)(H4,6,7,8)
InChI key
VVHOUVWJCQOYGG-UHFFFAOYSA-N
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A Torremans et al.
Brain research, 1008(1), 107-112 (2004-04-15)
Uremic retention solutes possibly contribute to neuronal hypoxia/ischemia and its consequences in patients with renal failure. We examined the in vitro effects of several uremic retention solutes on murine central neurons under chemically induced metabolic hypoxia by application of sodium
Youri E C Taes et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23(4), 1330-1335 (2007-12-01)
Specific guanidino compounds have been described as uraemic toxins and their concentrations are increased in renal failure due to dimished glomerular filtration, whereas the guanidino compound creatine is used as a performance-enhancing substance in athletes. The present study investigates the
Michal Ciborowski et al.
PloS one, 7(2), e31982-e31982 (2012-03-03)
Abdominal aortic aneurysm (AAA) is a permanent and localized aortic dilation, defined as aortic diameter ≥3 cm. It is an asymptomatic but potentially fatal condition because progressive enlargement of the abdominal aorta is spontaneously evolving towards rupture.Biomarkers may help to
K Aoyagi et al.
Free radical research, 31(1), 59-65 (1999-09-17)
Guanidinosuccinic acid (GSA) is noted for its nitric oxide (NO) mimicking actions such as vasodilatation and activation of the N-methyl-D-aspartate (NMDA) receptor. We have reported that GSA is the product of argininosuccinate (ASA) and some reactive oxygen species, mainly the
Burton D Cohen
Molecular and cellular biochemistry, 298(1-2), 195-198 (2006-12-01)
Guanidinosuccinic acid is an aberrant metabolite isolated 40 years ago in the blood and urine of uremic subjects and a suspect in the toxicity associated with renal failure. It plays a minor role in the bleeding diathesis of uremia, contributes
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