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D0380

Sigma-Aldrich

Nε-DNP-L-lysine hydrochloride

Synonym(s):

Nε-(2,4-Dinitrophenyl)-L-lysine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16N4O6 · HCl
CAS Number:
14401-10-6
Molecular Weight:
348.74
EC Number:
238-366-0
MDL number:
MFCD00036383
UNSPSC Code:
12352200
PubChem Substance ID:
24893228

form

powder

storage temp.

−20°C

SMILES string

OC([C@@H](N)CCCCNC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1)=O.[H]Cl

InChI

1S/C12H16N4O6.ClH/c13-9(12(17)18)3-1-2-6-14-10-5-4-8(15(19)20)7-11(10)16(21)22;/h4-5,7,9,14H,1-3,6,13H2,(H,17,18);1H

InChI key

VDVXDUOPLKVMMM-UHFFFAOYSA-N

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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G P Holland et al.
Journal of immunological methods, 138(2), 245-255 (1991-04-25)
The influence of the epitope density of the antigen on antibody affinity values determined by fluid- and solid-phase immunoassays was assessed. The affinity of the interaction of a panel of monoclonal anti-DNP antibodies of different affinities (as determined by equilibrium
K Maeyama et al.
Analytical biochemistry, 194(2), 316-325 (1991-05-01)
In rat basophilic leukemia cells (RBL-2H3), a tumor analogue of mast cells, the aggregation of IgE receptors initiates increase in the intracellular concentration of calcium ([Ca2+]i), monitored with the fluorescent Ca probe fura-2, and finally results in histamine secretion. In
R A Hatz et al.
Gastroenterology, 98(4), 894-900 (1990-04-01)
The capacity of the stomach to participate in anaphylaxis induced by the hapten N,N'-di-2,4,dinitrophenyllysine (di-DNP-lysine) was examined in BDF1 female mice immunized with dinitrophenylated Ascaris suum extract. Immunized animals underwent laparotomy and nontraumatic pyloric occlusion using a microvascular clamp. Following
R Bredehorst et al.
Analytical biochemistry, 193(2), 272-279 (1991-03-02)
We developed a novel trifunctional carrier molecule for the synthesis of hapten-fluorophore conjugates as reporter molecules in immunoassays. This carrier eliminates some of the disadvantages associated with currently used fluorophore-labeling procedures including high nonspecific binding. The backbone of the carrier
P L Amlot et al.
Clinical and experimental immunology, 64(1), 125-135 (1986-04-01)
Thymus-independent (TI) and thymus-dependent (TD) primary immune responses were measured in 67 controls and 13 bone marrow transplant (BMT) recipients treated with cyclosporine (CSP) by immunizing with a synthetic antigen (DNP-Ficoll) and keyhole limpet haemocyanin (KLH). DNP-Ficoll induced similar TI
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