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C7786

Sigma-Aldrich

Conalbumin from chicken egg white

BioReagent, suitable for cell culture

Synonym(s):

Ovotransferrin

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About This Item

CAS Number:
1391-06-6
EC Number:
215-727-0
MDL number:
MFCD00130856
UNSPSC Code:
12352202
NACRES:
NA.75

biological source

chicken egg white

product line

BioReagent

form

powder

concentration

80-100 % protein Biuret

technique(s)

cell culture | mammalian: suitable

solubility

water: 25 mg/mL, clear to slightly hazy, pink

cation traces

Fe: ≤0.02%

UniProt accession no.

P02789

shipped in

ambient

storage temp.

−20°C

Gene Information

chicken ... TF(396241)

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General description

Conalbumin, also referred to as ovotransferrin, is encoded by the avian transferrin gene in the oviduct. It is a monomeric glycoprotein consisting of 686 amino acids and is a member of transferrin family. Conalbumin is one among the abundant proteins present in the chicken egg white.

Application

Conalbumin has been used:
  • as a constituent of Leibovitz 15 (L15) medium involved in preparation of primary neuronal cultures
  • to study its adsorption property on a metal surface in the presence of an external electric potential
  • to determine its adsorption isotherms in anion exchange chromatography by multivariate analysis

Biochem/physiol Actions

Conablumin (aka ovotransferrin) is a glycoprotein derived from egg white with a sequence similar to serum transferrin, but with a different glycosylation pattern. It is a strong iron binder with antiviral and antibacterial activities.
Conalbumin facilitates the transport of iron to the developing embryo. It exhibits anti-microbial activity thus, conalbumin is used in various applications such as infant formula ingredient, a food additive, and an antimicrobial agent for enhancing animal health. In addition, it also acts as an antifungal, antiviral, anticancer, antioxidative, antihypertensive and immunoregulatory agent.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Preparation of anionic polyelectrolyte modified magnetic nanoparticles for rapid and efficient separation of lysozyme from egg white
Chen J, et al.
Journal of Chromatography A, 1388, 43-51 (2015)
Ovotransferrin: Structure, bioactivities, and preparation
Wu J and Acero-Lopez A
Food Research International, 46(2), 480-487 (2012)
Adsorption characteristics of various proteins on a metal surface in the presence of an external electric potential
Htwe Ei, et al.
Colloids and Surfaces. B, Biointerfaces, 166, 262-268 (2018)
İrem Lütfiye Atasoy et al.
Journal of chemical neuroanatomy, 80, 19-26 (2016-12-05)
Intracellular aggregation of hyperphosphorylated tau in neurofibrillary tangles (NFTs) is a major neuropathological hallmark of taupathies such as Alzheimer's disease. Okadaic acid (OKA) is a potent inhibitor of PP2A, leading to abnormal tau phosphorylation. Brain-derived neurotrophic factor (BDNF) is a
Chia-Hsin Lee et al.
The Analyst, 136(7), 1481-1487 (2011-01-27)
A ZrO(2) nanoparticles (ZrO(2)NPs)-coated column was prepared through a sol-gel process using zirconium(iv) oxychloride, which reacted with silanol groups of the fused-silica capillary. The condensation reaction was carried out at 350 °C for 8 h. Electroosmotic flow (EOF) measurements and
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Chromatograms

application for HPLC

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