B5309
Lys-Lys-(Hyp3,β-(2-thienyl)-Ala5,8,D-Phe7)-Bradykinin
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About This Item
Empirical Formula (Hill Notation):
C62H95N19O14S2
Molecular Weight:
1394.67
MDL number:
UNSPSC Code:
12352200
composition
Peptide content, ≥70%
storage temp.
−20°C
SMILES string
NCCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N2C[C@H](O)C[C@H]2C(=O)NCC(=O)N[C@@H](Cc3cccs3)C(=O)N[C@@H](CO)C(=O)N[C@H](Cc4ccccc4)C(=O)N[C@@H](Cc5cccs5)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Amino Acid Sequence
Lys-Lys-Arg-Pro-Hyp-Gly-β-(2-thienyl)-Ala-Ser-D-Phe-β-(2-thienyl)-Ala-Arg-OH
Biochem/physiol Actions
An analog of bradykinin which is a specific inhibitor of five different actions of bradykinin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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T Griesbacher et al.
British journal of pharmacology, 92(2), 333-340 (1987-10-01)
1 The inhibition of the bradykinin-induced plasma extravasation by six bradykinin (Bk) antagonists was tested on rabbit skin. All of them showed inhibitory effects without an agonistic action in the does used. B4310 (Lys-Lys-3-Hyp-5,8-Thi-7-DPhe-Bk) was the most active antagonist and
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