A3160

Acetylsalicylic acid

analytical standard

• Synonym(s): 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Linear Formula: 2-(CH₃CO₂)C₆H₄CO₂H
• CAS Number: 50-78-2
• Molecular Weight: 180.16
• Beilstein: 779271
• EC Number: 200-064-1
• MDL number: MFCD00002430
• UNSPSC Code: 12352106
• PubChem Substance ID: 24890723
• NACRES: NA.21

Properties

• grade: analytical standard
• form: powder
• packaging: vial of 500 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 134-136 °C (lit.)
• application(s): forensics and toxicology; pharmaceutical; veterinary
• SMILES string: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• InChI key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Gene Information: human ... ITGA2B(3674) , PTGS1(5742) , PTGS2(5743)

Description

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Packaging

Supplied in amber screw-cap vials

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 482.0 °F
• Flash Point(C): 250 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves