90771
Poly(maleic anhydride-alt-1-tetradecene), 3-(dimethylamino)-1-propylamine derivative
BioReagent, for molecular biology
Synonym(s):
PMAL®-C12
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grade
for molecular biology
description
zwitterionic
product line
BioReagent
form
solid
λ
0.1 % in H2O
UV absorption
λ: 260 nm Amax: 0.400
λ: 280 nm Amax: 0.150
storage temp.
−20°C
Application
Use of "Amphipols" for delivering of membrane proteins to lipid bilayers, as activity support of membrane enzymes.
Analysis Note
enzyme traces DNases, RNases, and phosphatases not detectable
Legal Information
PMAL is a registered trademark of Affymetrix, Inc.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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J K Nagy et al.
FEBS letters, 501(2-3), 115-120 (2001-07-27)
Data are presented which suggest that a class of amphiphilic polymers known as 'amphipols' may serve as a vehicle for delivering complex integral membrane proteins into membranes. The integral membrane protein diacylglycerol kinase (DAGK) was maintained in soluble form by
Bonnie M Gorzelle et al.
Journal of the American Chemical Society, 124(39), 11594-11595 (2002-09-26)
Amphipathic polymers ("amphipols") were introduced several years ago (Tribet, C.; Audebert, R.; Popot, J.-L. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 15047-15050) as an alternative method for solubilizing integral membrane proteins in stable, nativelike conformations. However, direct maintenance of full
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