The molecular weight of this product has not been determined. Various publications suggest that this enzyme is a dimer with an approximate molecular weight of 110,000 daltons. Each subunit is reported to be 57,000 daltons. See the link below for additional information:
https://pubmed.ncbi.nlm.nih.gov/7117244/
45299
Epoxide Hydrolase from Rhodococcus rhodochrous
lyophilized powder, beige, ≥0.2 U/g
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
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Biochem/physiol Actions
Epoxide hydrolase is an enantioselective catalyst for the hydrolytic kinetic resolution of epoxides.[1]
Unit Definition
1 U corresponds to the amount of enzymes which hydrolizes 1 μmol (S)-NEPC [(2S,3S)-trans-3-phenyl-2-oxiranylmethyl-4-nitrophenyl carbonate, Prod. No. 04088] per minute at pH 8.0 and 25 °C
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hechtberger, P.
Tetrahedron Asymmetry, 4, 1161-1161 (1993)
Mischitz, M., et al.
Tetrahedron Asymmetry, 7, 2041-2041 (1996)
E N Jacobsen
Accounts of chemical research, 33(6), 421-431 (2000-07-13)
The discovery of the metal salen-catalyzed asymmetric ring-opening (ARO) of epoxides is chronicled. A screening approach was adopted for the identification of catalysts for the addition of TMSN(3) to meso-epoxides, and the chiral (salen)CrN(3) complex was identified as optimal. Kinetic
Ana W Y Cheong et al.
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Regulation of angiogenesis is critical for many diseases. Specifically, pathological retinal neovascularization, a major cause of blindness, is suppressed with dietary ω3-long-chain polyunsaturated fatty acids (ω3LCPUFAs) through antiangiogenic metabolites of cyclooxygenase and lipoxygenase. Cytochrome P450 epoxygenases (CYP2C8) also metabolize LCPUFAs
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Hello, I was wondering if you could please let me know the molecular weight of this enzyme from Rhodococcus rhodochrous.
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