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270482

Sigma-Aldrich

2-Methoxyethanol

suitable for HPLC, ≥99.9%

Synonym(s):

Ethylene glycol monomethyl ether, Methyl glycol

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About This Item

Linear Formula:
CH3OCH2CH2OH
CAS Number:
109-86-4
Molecular Weight:
76.09
Beilstein:
1731074
EC Number:
203-713-7
MDL number:
MFCD00002867
UNSPSC Code:
12190000
PubChem Substance ID:
329752943
NACRES:
NA.21

vapor density

2.62 (vs air)

vapor pressure

6.17 mmHg ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

548 °F

purified by

glass distillation

expl. lim.

24.5 %

technique(s)

HPLC: suitable

impurities

<0.050% water

evapn. residue

<0.0005%

refractive index

n20/D 1.402 (lit.)

pH

5.0-7.0 (25 °C)

bp

124-125 °C (lit.)

mp

−85 °C (lit.)

density

0.965 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 213 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 260 nm Amax: 0.05
λ: 300-400 nm Amax: 0.01

application(s)

food and beverages

SMILES string

COCCO

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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General description

This solvent is glass distilled, submicron filtered and subjected to rigorous specification testing to provide lot-to-lot consistency.

Application

Designed for use with HPLC instrumentation and organic synthesis applications.
Used in the LC-MS of rat urine samples for determination of 2-methoxyethanol.

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B - STOT RE 2 - STOT SE 1

Target Organs

Immune system, thymus

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F - closed cup

Flash Point(C)

40 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Robert A Hartman et al.
Journal of biomechanics, 45(2), 382-385 (2011-11-22)
Intervertebral disc degeneration, a leading cause of low back pain, poses a significant socioeconomic burden with a broad array of costly treatment options. Mechanical loading is important in disease progression and treatment. Connecting mechanics and biology is critical for determining
Conductometric, viscometric, and spectroscopic investigations on the solvation phenomena of alkali-metal ions and ion pairs in 2-methoxyethanol.
Das B and Hazra DK.
The Journal of Physical Chemistry, 99(1), 269-273 (1995)
Makoto Takei et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 643-652 (2010-07-10)
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order
Anna Maria Piras et al.
International journal of pharmaceutics, 357(1-2), 260-271 (2008-03-04)
The preparation of novel biocompatible polymeric nanoconstructs suitable to load sensitive bioactive protein agents is reported. Nanoparticles were prepared as based on hybrid polymeric matrices consisting of synthetic bioerodible alternating copolymers of maleic anhydride and n-butylvinylether hemiesterified with 2-methoxyethanol and
Alberto Dessy et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 43(1-2), 57-64 (2011-03-30)
In the present work polymeric nanoparticles based on Poly (maleic anhydride-alt-butyl vinyl ether) 5% grafted with m-PEG (2000) and 95% grafted with 2-methoxyethanol (VAM41-PEG) were loaded with human hemoglobin (Hb) and characterized from a physicochemical point of view. The assessment
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