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F8639

Supelco

Famprofazone

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C24H31N3O
CAS Number:
22881-35-2
Molecular Weight:
377.52
EC Number:
245-284-9
MDL number:
MFCD00079304
UNSPSC Code:
41116107
PubChem Substance ID:
329799771
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC(C)C1=C(CN(C)C(C)Cc2ccccc2)N(C)N(c3ccccc3)C1=O

InChI

1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3

InChI key

GNUXVOXXWGNPIV-UHFFFAOYSA-N

General description

Famprofazone is a pyrazole derivative and belongs to the class of non-steroidal anti-inflammatory drugs. It is widely used as an analgesic and antipyretic in medical applications.

Application

Famprofazone may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
128F0476

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E S Oh et al.
Xenobiotica; the fate of foreign compounds in biological systems, 22(3), 377-384 (1992-03-01)
1. To obtain further evidence for the metabolic formation of methamphetamine from famprofazone in man, concentrations of methamphetamine in plasma, as well as in urine, were measured by g.l.c. In addition, intact famprofazone and famprofazone N-oxide were analysed in the
Identification of new urinary metabolites of famprofazone in humans
Journal of Analytical Toxicology, 22(1), 55-60 (1998)
Ying Lung Tseng et al.
Journal of forensic sciences, 52(2), 479-486 (2007-02-24)
During a sport competition event in Taiwan, one urine specimen was found positive for both methamphetamine (2688 ng/mL) and amphetamine (462 ng/mL). The specimen donor claimed that she had taken Gewolen (a nonprescription drug manufactured in Taiwan) for treating abdominal
Elisangela de Souza Santos et al.
Talanta, 191, 545-552 (2018-09-29)
Forensic toxicologists typically work with body fluids, such as blood and urine, or visceral tissues. The analysis of alternative samples, such as bone marrow, can be requested when the commonly used samples are unavailable due to an extended time lapse
F Musshoff
Drug metabolism reviews, 32(1), 15-44 (2000-03-11)
The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution of urine samples and the knowledge about legitimate and illicit sources
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