79840

N-Phthaloyl-L-glutamic acid

purum, ≥98.0% (T)

• Synonym(s): PhGA
• Empirical Formula (Hill Notation): C₁₃H₁₁NO₆
• CAS Number: 340-90-9
• Molecular Weight: 277.23
• Beilstein: 90136
• MDL number: MFCD00066476
• UNSPSC Code: 12352200
• PubChem Substance ID: 329768646

Properties

• grade: purum
• Assay: ≥98.0% (T)
• optical activity: [α]20/D −48±2°, c = 3% in dioxane
• mp: 160-162 °C (lit.); 160-162 °C
• application(s): peptide synthesis
• SMILES string: OC(=O)CC[C@H](N1C(=O)c2ccccc2C1=O)C(O)=O
• InChI: 1S/C13H11NO6/c15-10(16)6-5-9(13(19)20)14-11(17)7-3-1-2-4-8(7)12(14)18/h1-4,9H,5-6H2,(H,15,16)(H,19,20)/t9-/m0/s1
• InChI key: FEFFSKLJNYRHQN-VIFPVBQESA-N

Description

Other Notes

N-protected derivative of L-glutamic acid. The anhydride (prepared with DCCI or Ac₂O without racemization) is used for γ-L-glutamylations; The phthaloyl protection can be removed mildly

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves