03951
N-Ethylformamide
≥99.0% (GC)
Synonym(s):
N-Formylethylamine
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About This Item
Linear Formula:
HCONHC2H5
CAS Number:
Molecular Weight:
73.09
Beilstein:
1737860
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
100
500
Assay
≥99.0% (GC)
form
liquid
refractive index
n20/D 1.432
bp
202-204 °C
density
0.950 g/mL at 20 °C (lit.)
SMILES string
CCNC=O
InChI
1S/C3H7NO/c1-2-4-3-5/h3H,2H2,1H3,(H,4,5)
InChI key
KERBAAIBDHEFDD-UHFFFAOYSA-N
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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M R Del Carratore et al.
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Chemical research in toxicology, 3(4), 357-362 (1990-07-01)
Hepatotoxic formamides such as N-methylformamide (NMF) and N,N-dimethylformamide (DMF) are metabolized in vivo to N-acetyl-S-(N-methylcarbamoyl)cysteine via oxidation at the formyl carbon, which yields a reactive intermediate. The hypothesis was tested that this biotransformation route can be studied in vitro with
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S P Langdon et al.
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The induction of terminal differentiation in tumour cells represents a possible therapeutic strategy for treating cancer. The alkylformamides are 1 group of experimental compounds which have been shown to induce terminal differentiation in human HL-60 leukemia and murine Friend erythroleukemia
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The Journal of pharmacology and experimental therapeutics, 240(1), 265-270 (1987-01-01)
The hepatotoxicity and metabolism of the following close analogs of the hepatotoxic antitumor agent N-methylformamide (NMF) were investigated in CBA/CA mice: N-ethylformamide (NEF), dimethylformamide (DMF), formamide and N-methylacetamide (NMA). Apart from NMF only NEF was potently hepatotoxic as measured by
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