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FCMAB312F

Sigma-Aldrich

Milli-Mark® Anti-Galactocerebroside-FITC Antibody, clone mGalC

clone mGalC, Milli-Mark®, from mouse

Synonym(s):

Galactoceramide, Galactocerebroside, Galactosylceramide, GalC

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

FITC conjugate

antibody form

purified antibody

antibody product type

primary antibodies

clone

mGalC, monoclonal

species reactivity

rat, human, mouse, rabbit, chicken

species reactivity (predicted by homology)

bovine (immunogen homology)

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG3

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GALC(2581)

General description

Galactocerebroside (GalC) is a major galactosphingolipid of myelin which plays a role in myelination. GalC is a very useful, specific marker for oligodendroglial lineage.

Specificity

Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically with oligodendrocytes and Schwann cells.

Immunogen

Synaptic plasma membranes from bovine hippocampus.

Application

Detect Galactocerebroside using this Milli-Mark Anti-Galactocerebroside-FITC Antibody, clone mGalC validated for use in FC.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Quality

Evaluated by flow cytometry using PC-12 cells.

Physical form

Protein A purified
Purified mouse monoclonal IgG3 conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Storage and Stability

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
PC-12 cells

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Denis Avey et al.
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Molecular and behavioral responses to opioids are thought to be primarily mediated by neurons, although there is accumulating evidence that other cell types play a prominent role in drug addiction. To investigate cell-type-specific opioid responses, we performed single-cell RNA sequencing
Emilio Merheb et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(40) (2021-09-30)
RNA polymerase (Pol) III synthesizes abundant short noncoding RNAs that have essential functions in protein synthesis, secretion, and other processes. Despite the ubiquitous functions of these RNAs, mutations in Pol III subunits cause Pol III-related leukodystrophy, an early-onset neurodegenerative disease.

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