1.04760

Iodine

purified by sublimation, EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP

• Synonym(s): Iodine
• Empirical Formula (Hill Notation): I₂
• CAS Number: 7553-56-2
• Molecular Weight: 253.81
• MDL number: MFCD00011355
• UNSPSC Code: 12141916
• EC Index Number: 231-442-4

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• vapor pressure: 0.41 hPa ( 25 °C)
• product line: EMPROVE^® ESSENTIAL
• form: solid
• potency: 14000 mg/kg LD₅₀, oral (Rat); 1425 mg/kg LD₅₀, skin (Rabbit)
• pH: 5.4 ( in H₂O, saturated solution)
• kinematic viscosity: 0.57 cSt(116 °C) (liquid)
• bp: 185 °C/1013 hPa
• mp: 114 °C
• density: 4.93 g/cm³ at 20 °C
• application(s): pharmaceutical; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/I2/c1-2
• InChI key: PNDPGZBMCMUPRI-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Iodine is used to treat and prevent iodine deficiency and as an antiseptic. As an antiseptic it may be used on wounds that are wet or to disinfect the skin before surgery.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302 + H312 + H332,H315,H319,H335,H372,H400
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Respiratory system, Thyroid
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable