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880270C

Avanti

C8 PEG5000 Ceramide

Avanti Research™ - A Croda Brand 880270C

Synonym(s):

N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)5000]}

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About This Item

CAS Number:
212116-76-2
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880270C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880270C

concentration

10 mg/mL (880270C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)COC(CCC([(OCH2CH2)113OCH3])=O)=O

General description

Ceramides are prominent lipids of lamellar sheets in stratum corneum. They are heterogeneous molecules belonging to the group of sphingolipids.

Biochem/physiol Actions

Poly(ethylene glycol) (PEG) conjugated ceramides are known to influence stabilized plasmid-lipid particle formation (SPLP). The size of the polymer and length of the acyl chain affects the transfection potency of SPLP.

Packaging

5 mL Clear Glass Sealed Ampule (880270C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ceramides and skin function
Coderch L, et al.
American Journal of Clinical Dermatology, 4(2), 107-129 (2003)
Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties
Mok KWC, et al.
Biochimica et Biophysica Acta - Biomembranes, 1419(2), 137-150 (1999)
Hudson P Pace et al.
Analytical chemistry, 90(21), 13065-13072 (2018-10-24)
Over the last two decades, supported lipid bilayers (SLBs) have been extensively used as model systems to study cell membrane structure and function. While SLBs have been traditionally produced from simple lipid mixtures, there has been a recent surge in

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