T76201

Trimethylene oxide

97%

• Synonym(s): 1,3-Epoxypropane, 1,3-Propylene oxide, Cyclooxabutane, Oxacyclobutane, Oxetane
• Empirical Formula (Hill Notation): C₃H₆O
• CAS Number: 503-30-0
• Molecular Weight: 58.08
• Beilstein: 102382
• EC Number: 207-964-3
• MDL number: MFCD00005167
• UNSPSC Code: 12352100
• PubChem Substance ID: 24900463
• NACRES: NA.22

Properties

• vapor pressure: 5.09 psi ( 20 °C)
• Assay: 97%
• refractive index: n20/D 1.388-1.396; n20/D 1.392 (lit.)
• bp: 50 °C (lit.)
• density: 0.893 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: C1COC1
• InChI: 1S/C3H6O/c1-2-4-3-1/h1-3H2
• InChI key: AHHWIHXENZJRFG-UHFFFAOYSA-N

Description

Application

• Trimethylene oxide is a strained cyclic ether which can be used to replace carbonyl / gem-dimethyl groups during molecular modelling of bioactive molecules.
• It can be incorporated in various bioactive molecule and drug substances for its improved physicochemical properties, via novel C-H activation methods.
• Trimethylene oxide can also be used in the synthesis of poly(trimethylene oxide) and related polymer electrolytes.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332
• Precautionary Statements: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): -4.0 °F - closed cup
• Flash Point(C): -20 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves