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About This Item
Empirical Formula (Hill Notation):
C14H26N2O6
Molecular Weight:
318.37
UNSPSC Code:
12352106
PubChem Substance ID:
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Assay
≥95%
form
solid or liquid
refractive index
n/D 1.4567
density
1.1544 g/mL
functional group
amine
carboxylic acid
Application
This hydroxylamine derivative readily reacts with potassium acyltrifluoroborates (KATs) to chemoselectively form amide bonds under aqueous conditions. Once incorporated into peptides, the Boc-hydroxylamine is stable to unprotected primary amines and conditions needed for ligation, deprotection, or Fmoc cleavage. The presence of the hydroxylamine on your peptide or protein enables the chemoselective conjugation of any of the several KAT analogues introduced collaboratively with the Jeff Bode Research Group.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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Bode Group creates N-mesityl-NHC catalysts for enantioselective annulations and SnAP reagents for one-pot aldehyde conversion into N-heterocycles.
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