861847
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
97%
Synonym(s):
FCCP, Mesoxalonitrile 4-trifluoromethoxyphenylhydrazone
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About This Item
Linear Formula:
CF3OC6H4NHN=C(CN)2
CAS Number:
Molecular Weight:
254.17
Beilstein:
664446
EC Number:
MDL number:
UNSPSC Code:
12352103
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Assay
97%
mp
174-175 °C (dec.) (lit.)
SMILES string
FC(F)(F)Oc1ccc(N\N=C(/C#N)C#N)cc1
InChI
1S/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H
InChI key
BMZRVOVNUMQTIN-UHFFFAOYSA-N
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Lin Du et al.
Journal of natural products, 73(11), 1868-1872 (2010-10-12)
The mammea-type coumarin mammea E/BB (1) was found to inhibit both hypoxia-induced and iron chelator-induced hypoxia-inducible factor-1 (HIF-1) activation in human breast tumor T47D cells with IC(50) values of 0.96 and 0.89 μM, respectively. Compound 1 suppressed the hypoxic induction
Dawn A Delfín et al.
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BTB 06237 (2-[(2,4-dichloro-5-methylphenyl)sulfanyl]-1,3-dinitro-5-(trifluoromethyl) benzene), a compound previously identified through QSAR pharmacophore development and a virtual screen of the Maybridge database, possesses potent and selective activity against Leishmania parasites. In the present study, several analogs of BTB 06237 were synthesized and
A Magge et al.
Journal of applied microbiology, 106(3), 814-824 (2009-02-04)
To determine roles of coats in staining Bacillus subtilis spores, and whether spores have membrane potential. Staining by four dyes and autofluorescence of B. subtilis spores that lack some (cotE, gerE) or most (cotE gerE) coat protein was measured. Wild-type
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Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17)
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify compounds
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