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791334

Sigma-Aldrich

Silica, nanoparticle dispersion in water

<30 nm (DLS), triethoxylpropylaminosilane functionalized

Synonym(s):

NH2 functionalized NPs

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23

form

dispersion
nanoparticles

shelf life

1 yr

concentration

in water (Dispersion)

particle size

<30 nm (DLS)

density

1.158 g/mL at 25 °C

functional group

amine

storage temp.

20-25°C

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Application

Silica nanoparticles play a crucial role in biotechnology including bone engineering and drug delivery. The amino functionality present on the surface of these materials provides a synthetic handle for further modification and conjugation to target moieties. Amino functionalized silica particles can be used for applicaitons including in vivo gene delivery; nanocomposite formation, and formation of biofilms.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314,H317

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Kazuki Murai et al.
Physical chemistry chemical physics : PCCP, 15(27), 11454-11460 (2013-06-12)
We investigated the drug releasing behavior of a novel nanocarrier system, utilizing a peptide to act as a nanogate to the mesopore, on a mesoporous silica nanoparticle. The surface peptide on mesoporous silica displayed pH-dependant mesopore cap-uncap switching behavior, enabled
Preparation and characterization of epoxy composites filled with functionalized nanosilica particles obtained via sol-gel process
Kang, S..;
Polymer, 42(3), 879-887 (2000)
Dhruba J Bharali et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(32), 11539-11544 (2005-07-30)
This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as a nonviral vector for efficient in vivo gene delivery. Highly monodispersed, stable aqueous suspension of nanoparticles, surface-functionalized with amino groups for binding of DNA, were prepared and
Pingli He et al.
Langmuir : the ACS journal of surfaces and colloids, 20(3), 722-729 (2005-03-19)
Heme protein hemoglobin (Hb) or myoglobin (Mb) and silica nanoparticles in a variety of charge states were assembled layer-by-layer into films on solid surfaces to investigate the driving forces for film assembly. Cyclic voltammetry (CV), quartz crystal microbalance (QCM), X-ray
Indrajit Roy et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(2), 279-284 (2005-01-05)
This article reports a multidisciplinary approach to produce fluorescently labeled organically modified silica nanoparticles as a nonviral vector for gene delivery and biophotonics methods to optically monitor intracellular trafficking and gene transfection. Highly monodispersed, stable aqueous suspensions of organically modified
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