Poly(L-lactide); PLLA; is a semi-crystalline biodegradable polymer used in drug delivery; the azide functionality is commonly utilized in copper mediated ligation. PLLA is soluble in toluene, THF, CHCl3, and CH2Cl2; insoluble in methanol; hexane and ether.
Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.
In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.
Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.
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