549800

4-Bromo-2,3-dimethylanisole

96%

• Linear Formula: Br(CH₃)₂C₆H₂OCH₃
• CAS Number: 50638-48-7
• Molecular Weight: 215.09
• MDL number: MFCD01652199
• UNSPSC Code: 12352100
• PubChem Substance ID: 24874725

Properties

• Assay: 96%
• refractive index: n20/D 1.566 (lit.)
• bp: 197 °C (lit.)
• density: 1.36 g/mL at 25 °C (lit.)
• SMILES string: COc1ccc(Br)c(C)c1C
• InChI: 1S/C9H11BrO/c1-6-7(2)9(11-3)5-4-8(6)10/h4-5H,1-3H3
• InChI key: WOWNZZYJCUUIFC-UHFFFAOYSA-N

Description

General description

4-Bromo-2,3-dimethylanisole can be prepared from 2,3-dimethylanisole via bromination using N-bromosuccinimide-acetonitrile (NBS-CH₃CN) system.

Application

4-Bromo-2,3-dimethylanisole may be used in the preparation of:

• 4,6-Dibromo-2,3-dimethylanisole via bromination using NBS-CH₃CN system.
• 4-Methoxy-2,2′,3,3′-tetramethyldiphenyl ether by reacting with 2,3-dimethylphenol.
• A novel arylsulfonamide derivative with potent glucocorticoid receptor (GR) agonist activity.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves