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Sigma-Aldrich

Silver(I) sulfadiazine

98%

Synonym(s):

Silver sulfadiazine, Sulfadiazine silver

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About This Item

Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
22199-08-2
Molecular Weight:
357.14
EC Number:
244-834-5
MDL number:
MFCD00072101
UNSPSC Code:
12352302
PubChem Substance ID:
24871745
NACRES:
NA.23

Assay

98%

form

powder

mp

285 °C (dec.) (lit.)

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

UEJSSZHHYBHCEL-UHFFFAOYSA-N

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Application

Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Certificates of Analysis (COA)

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Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application
Fajardo AR, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 33(2), 588-595 (2013)
Chia-Yu Chu et al.
PloS one, 7(6), e38360-e38360 (2012-06-14)
Silver nanoparticles supported on nanoscale silicate platelets (AgNP/NSP) possess interesting properties, including a large surface area and high biocide effectiveness. The nanohybrid of AgNP/NSP at a weight ratio 7/93 contains 5-nm Ag particles supported on the surface of platelets with
Steven L Percival et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20(5), 647-657 (2012-09-19)
Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the innate barrier function of the skin and dermal appendages, facilitating the development of microbial communities, referred to as biofilms, within the wound environment. Microbial
Vincenzina Monzillo et al.
The new microbiologica, 35(2), 175-182 (2012-06-19)
The aim of this study was to compare the in vitro activity and the impact on bacterial adhesion of two different catheters, one impregnated with chlorhexidine-silver sulfadiazine (C-SS) and the other not impregnated with antibacterial agents. The antimicrobial coating prevented
[Modern possibilities of the local treatment of children with burn wounds].
L I Budkevich et al.
Khirurgiia, (10)(10), 48-51 (2012-12-14)
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