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301515

Sigma-Aldrich

N-Tritylglycine

98%

Synonym(s):

N-(Triphenylmethyl)glycine

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About This Item

Linear Formula:
(C6H5)3CNHCH2CO2H
CAS Number:
5893-05-0
Molecular Weight:
317.38
MDL number:
MFCD00004276
UNSPSC Code:
12352209
PubChem Substance ID:
24858195
NACRES:
NA.22

Assay

98%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

SMILES string

OC(=O)CNC(c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C21H19NO2/c23-20(24)16-22-21(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,22H,16H2,(H,23,24)

InChI key

XUXRXWLKUYPGMZ-UHFFFAOYSA-N

Application

N-protected glycine for the preparation of peptides.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Synthesis, 219-219 (1984)
Tetrahedron, 40, 1869-1869 (1984)
Atsushi Tamura et al.
Journal of biomaterials science. Polymer edition, 28(10-12), 1124-1139 (2017-03-17)
We developed stimuli-labile polyrotaxanes (PRXs) composed of β-cyclodextrin (β-CD), Pluronic as an axle polymer, and acid-cleavable N-triphenylmethyl groups as bulky stopper molecules, and found that the PRXs are potent therapeutics for Niemann-Pick type C disease, because the PRX can effectively
Hiraku Onishi et al.
Biological & pharmaceutical bulletin, 37(10), 1641-1649 (2014-10-03)
Chondroitin sulfate-glycyl-prednisolone conjugate (CS-GP) was previously demonstrated to exhibit superior anti-arthritic effects compared to prednisolone (PD) alone. In this study, CS-GP was examined for its pharmacokinetic features and tropism for inflammatory joints using rats with adjuvant-induced arthritis in order to

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