283363

3-Fluoro-4-nitrotoluene

99%

• Linear Formula: CH₃C₆H₃(NO₂)F
• CAS Number: 446-34-4
• Molecular Weight: 155.13
• Beilstein: 2502584
• EC Number: 207-166-5
• MDL number: MFCD00007053
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857103

Properties

• Assay: 99%
• form: solid
• bp: 97-98 °C/3 mmHg (lit.)
• mp: 52-55 °C (lit.)
• SMILES string: Cc1ccc(c(F)c1)[N+]([O-])=O
• InChI: 1S/C7H6FNO2/c1-5-2-3-7(9(10)11)6(8)4-5/h2-4H,1H3
• InChI key: WZMOWQCNPFDWPA-UHFFFAOYSA-N

Description

Application

3-Fluoro-4-nitrotoluene has been used in the preparation of IκB kinase (IKK) inhibitor, BMS [N¹-(1,8-dimethylimidazo[1,2-a]quinolin-4-yl)-ethane-1,2-diamine].

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332,H315,H319,H335
• Precautionary Statements: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves