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Key Documents

1345159

USP

Ioxaglic acid

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-(2-Hydroxyethyl)-2,4,6-triiodo-5-{2-[2,4,6-triiodo-3-(N-methylacetamido)-5-(methylcarbamoyl)benzamido]acetamido}isophthalamic acid

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About This Item

Empirical Formula (Hill Notation):
C24H21I6N5O8
CAS Number:
59017-64-0
Molecular Weight:
1268.88
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ioxaglic acid

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C24H21I6N5O8/c1-7(37)35(3)20-17(29)10(21(39)31-2)13(25)11(18(20)30)23(41)33-6-8(38)34-19-15(27)9(22(40)32-4-5-36)14(26)12(16(19)28)24(42)43/h36H,4-6H2,1-3H3,(H,31,39)(H,32,40)(H,33,41)(H,34,38)(H,42,43)

InChI key

TYYBFXNZMFNZJT-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ioxaglic acid USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Ioxaglate Meglumine and Ioxaglate Sodium Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rachel C Stewart et al.
Radiology, 266(1), 141-150 (2012-11-30)
To quantify the affinity of a cationic computed tomography (CT) contrast agent (CA(4+)) and that of an anionic contrast agent (ioxaglate) to glycosaminoglycans (GAGs) in ex vivo cartilage tissue explants and to characterize the in vivo diffusion kinetics of CA(4+)
Topical intranasal ioxaglate meglumine 39.3% and ioxaglate sodium 19.6% (Hexabrix) reduces the acute response to nasal challenge with allergen.
Shilpa Vishwanath et al.
The Journal of allergy and clinical immunology, 128(1), 219-221 (2011-03-19)
M J Turunen et al.
Journal of biomechanics, 45(3), 497-503 (2011-12-31)
In clinical arthrographic examination, strong hypertonic contrast agents are injected directly into the joint space. This may reduce the stiffness of articular cartilage, which is further hypothesized to lead to overload-induced cell death. We investigated the cell death in articular
Hye Jin Yoo et al.
Radiology, 261(3), 805-812 (2011-09-24)
To investigate the diagnostic potential of delayed contrast material-enhanced computed tomography (CT) of articular cartilage in quantification of glycosaminoglycan (GAG) concentration in normal and degenerated articular cartilage ex vivo by using a clinical CT scanner. This study was exempted by
Diana Constanze Lenhard et al.
Investigative radiology, 48(4), 175-182 (2012-12-25)
We analyzed renal kinetics and renal oxygenation in rats after administration of several classes and formulations of contrast agents (CAs) with a focus on the influence of osmolality and substance-specific properties. We investigated the renal kinetics of a nonionic, dimeric
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