U6381

Uridine

BioUltra, ≥99%

• Synonym(s): 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• Empirical Formula (Hill Notation): C₉H₁₂N₂O₆
• CAS Number: 58-96-8
• Molecular Weight: 244.20
• Beilstein: 754902
• EC Number: 200-407-5
• MDL number: MFCD00006526
• UNSPSC Code: 12352204
• PubChem Substance ID: 24900434
• NACRES: NA.26

Properties

• biological source: synthetic (organic)
• product line: BioUltra
• Assay: ≥99%
• form: powder
• impurities: ≤0.016% Phosphorus (P); ≤0.1% Insoluble matter
• ign. residue: ≤0.2%
• mp: 163-167 °C (lit.)
• solubility: H₂O: 0.1 M, clear, colorless
• cation traces: Al: ≤0.0005%; Ca: ≤0.01%; Cu: ≤0.0005%; Fe: ≤0.003%; K: ≤0.005%; Mg: ≤0.003%; NH₄⁺: ≤0.15%; Na: ≤0.02%; Pb: ≤0.005%; Zn: ≤0.0005%
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
• InChI key: DRTQHJPVMGBUCF-XVFCMESISA-N
• Gene Information: mouse ... Uck1(22245)

Description

General description

Uridine is a pyrimidine nucleoside which is crucial for the synthesis of RNA and membranes. It helps in normal cell function and growth by forming pyrimidine nucleotide -lipid conjugates.

Application

Uridine has been used to study the functional complementation of nucleoside hydrolase from a protozoan parasite and mammalian uridine phosphorylase on URH1 (uridine hydrolase) of Saccharomyces cerevisiae.
It has been used to check the effect of chronic uridine application on liver metabolism in mice.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves