PRS3985

Anti-Nicastrin (ab2) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-APH-2, Anti-Anterior pharynx defective 2, Anti-Nicastrin
• MDL number: MFCD03791914
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, rat, mouse
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q92542
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NCSTN(23385)

Description

General description

Nicastrin (NCSTN) is a transmembrane glycoprotein, that is located on chromosome 1q23.

Immunogen

a 18 amino acid peptide from near the center of human Nicastrin.

Application

Anti-Nicastrin has been used in western blotting.

Biochem/physiol Actions

Nicastrin (NCSTN) helps in the assembly of γ-secretase complex. It is associated with Alzheimer′s disease.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3985.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable