P1925
Protein A–Agarose macrobeads
aqueous suspension
Synonym(s):
Protein A resin
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form
aqueous suspension
Quality Level
extent of labeling
~6 mg per mL
matrix activation
cyanogen bromide
matrix spacer
1 atom
capacity
~6 mg/mL binding capacity (human IgG)
storage temp.
2-8°C
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General description
Protein A is an immunoglobulin (Ig)-binding protein that might be suitable for low-pressure antibody isolation.[1] It is used to purify large amounts of IgG[1] and binds to the Fc part of the antibody at the CH2–CH3 interface.[2] Protein A-agarose is used for affinity chromatography, antibody purification and characterization, and protein A, G and L resins.
Application
Protein A–Agarose macrobeads has been used in immunoprecipitation.[3] It has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer.
Physical form
Suspension in 0.9% NaCl containing 15Mm Sodium Azide
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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