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C8552

Sigma-Aldrich

Cytidine 5′-triphosphate disodium solution

HPLC purified, aqueous solution for RNA polymerase transcription

Synonym(s):

CTP-Na2

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About This Item

Empirical Formula (Hill Notation):
C9H16N3O14P3Na2
CAS Number:
81012-87-5
Molecular Weight:
529.14
MDL number:
MFCD00078193
UNSPSC Code:
41106305
PubChem Substance ID:
24893072
NACRES:
NA.52

Quality Level

300

form

liquid

concentration

95-105 mM in H2O (adjusted to pH 7 with Sodium Hydroxide)

color

colorless

foreign activity

DNase and RNase, none detected

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI

1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

InChI key

NFQMDTRPCFJJND-WFIJOQBCSA-L

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General description

Cytidine 5′-triphosphate (CTP) is a high-energy molecule and pyrimidine nucleoside triphosphate. It acts as a substrate for the RNA synthesis. CTP also acts as a coenzyme during the synthesis of glycerophospholipids and glycosylation of proteins. It is made up of cytidine and three phosphate groups and can be a potent phosphate source.

Application

For use in DNA-dependent RNA polymerase transcription

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sambrook, J., et al.
Molecular Cloning: A Laboratory Manual, 5-5 (1989)
Microwave-assisted hydrothermal rapid synthesis of amorphous calcium phosphate nanoparticles and hydroxyapatite microspheres using cytidine 5'-triphosphate disodium salt as a phosphate source
Zhao J, et al.
Materials Letters, 124, 208-211 (2014)
Xi Liu et al.
Anti-cancer drugs, 25(6), 690-703 (2014-03-29)
Treatment of mammalian cells with chemotherapeutic drugs can result in perturbations of nucleotide pools. Monitoring these perturbations in cultured tumor cells from human sources is useful for assessment of the effect of drug therapy and a better understanding of the

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