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A0138

Sigma-Aldrich

Aflatoxin G1

from Aspergillus flavus

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About This Item

Empirical Formula (Hill Notation):
C17H12O7
CAS Number:
1165-39-5
Molecular Weight:
328.27
Beilstein:
1299768
EC Number:
214-615-9
MDL number:
MFCD00005089
UNSPSC Code:
12352200
PubChem Substance ID:
24890402
NACRES:
NA.77

biological source

Aspergillus flavus

Quality Level

200

form

powder

storage temp.

2-8°C

SMILES string

COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCOC5=O)c14

InChI

1S/C17H12O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h3,5-6,8,17H,2,4H2,1H3

InChI key

XWIYFDMXXLINPU-UHFFFAOYSA-N

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General description

Aflatoxins are hepatotoxic metabolites, that are produced by molds, such as, Aspergillus flavus and Aspergillus parasiticus. They are naturally occurring poisonous carcinogens and the most widely known mycotoxins. They are associated with liver cancer and immune system suppression.

Application

Aflatoxin G1 from Aspergillus flavus has been used as a standard for the determination of aflatoxin in various samples.

Biochem/physiol Actions

Hepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus.

Warning

Possibly carcinogenic.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 1B - Muta. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Validation of simultaneous analysis method for determination of aflatoxins in olive oil by high performance liquid chromatographyfluorescence detector
Nabizadeh S, et al.
Journal of Food Safety and Hygiene, 1(2), 63-68 (2015)
Review of past and present research on Aflatoxin in Uganda
Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
The use of regenerated immunoaffinity columns for aflatoxins B1, B2, G1 and G2 in peanut confection
Iha Mh, et al.
Journal of Chromatography A, 1483, 1-7 (2017)
Review of past and present research on Aflatoxin in Uganda
Kaaya NA and Warren HL
African Journal of Food, Agriculture, Nutrition and Development, 5(1) (2005)
Haitao Shen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3222-3228 (2012-06-20)
Our previous studies showed intragastric administration of Aflatoxin G(1) (AFG(1)) could induce lung adenocarcinoma, which derived from alveolar type II cells (AT-II cells). AT-II cells contribute to Aflatoxin B(1) (AFB(1)) metabolism and also serve as the potential progenitor cells for
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