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Key Documents

MTGR85000

Millipore

Aervent®-50 Filter Unit 0.2 µm hydrophobic 1/4 in. HB/HB

pore size 0.2 μm

Synonym(s):

Aervent® 50 Capsule Filter, EPA Est. 041237-FRA-001

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About This Item

UNSPSC Code:
23151806
eCl@ss:
32031690
NACRES:
NB.24

material

PTFE membrane
polypropylene
polypropylene housing

Quality Level

sterility

irradiated
non-sterile

product line

Aervent®

feature

hydrophobic

manufacturer/tradename

Aervent®

parameter

2.1 bar max. differential pressure at 25 °C
4.1 bar max. inlet pressure (60 psi) at 25 °C

technique(s)

gas filtration: suitable

L

7.2 cm (2.84 in.)

W

2.4 in.

diam.

6.2 cm (2.4 in.)

filtration area

19.6 cm2

impurities

≤0.5 EU/mL (LAL test, Aqueous extraction)

gravimetric extractables

≤1.0 mg

matrix

Aervent®

pore size

0.2 μm pore size

bubble point

≥1100 mbar (16 psig), nitrogen with 60/40% IPA/water at 23 °C

fitting

inlet/outlet hose for 6.5-9.5 mm I.D. silicone tubing

shipped in

ambient

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General description

This Aervent® hydrophobic Capsule filter contain a 50 mm Aervent PTFE membrane in a bi-directionally supported polypropylene casing. This sterilizing-grade filter, with a 0.2 μm pore size and 19.6 cm2 filtration area, is designed for critical small scale gas line and air venting applications. The hydrophobic Aervent PTFE membrane within MTGR85000 provides high flow rates and throughput, low extractables and particle shedding, and broad chemical compatibility. For traceability and easy identification, each Aervent-50 filter is hot stamped with its catalogue number and lot number. Each Aervent®-50 Filter Unit 0.2 µm hydrophobic 1/4 in. HB/HB is integrity tested during manufacture.

Application

Typical Applications
  • Sterile venting of vessels and carboys
  • Autoclave vacuum break lines
  • Low volume sterile filtration of non-aqueous fluids
  • Small fermenter inlet and exhaust gas filtration

Preparation Note

Sterilization Method
10 autoclave cycles of 30 min @ 130 °C; not in-line steam sterilizable

Analysis Note

Bacterial Retention
Quantitative retention of 107 CFU/cm2Brevundimonas diminuta (ATCC® 19146) per ASTM F838-83 methodology
Gravimetric Extractables: in 70/30 % IPA/water

Other Notes

Directions for Use
  • Organism Retention: Microorganism
  • Mode of Action: Filtration (size exclusion)
  • Application: BioProcessing
  • Intended Use: Reduction or removal of microorganism/bioburden
  • Instructions for Use: Please refer Steam Sterilization & Integrity Testing Procedures guide and first page of Visual Inspection Guide
  • Storage Statement: Store in dry location
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.

Legal Information

AERVENT is a registered trademark of Merck KGaA, Darmstadt, Germany
ATCC is a registered trademark of American Type Culture Collection

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