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Key Documents

1.06529

Supelco

Sodium polyphosphate

(Graham′s salt) EMPLURA®

Synonym(s):

Sodium polyphosphate, Graham′s salt, Sodium metaphosphate

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About This Item

Linear Formula:
(NaPO3)n
CAS Number:
MDL number:
UNSPSC Code:
12352302
EC Index Number:
233-782-9
NACRES:
NA.21

Quality Level

product line

EMPLURA®

form

solid

potency

>2000 mg/kg LD50, oral (Rat)

concentration

≥68% ( P2O5, acidimetric)

pH

5.7 (20 °C, 10 g/L in H2O)

mp

550 °C

solubility

1000 g/L

density

2.5 g/cm3 at 20 °C

bulk density

1000 kg/m3

anion traces

chloride (Cl-): ≤0.02%

cation traces

Fe: ≤0.01%
heavy metals (as Pb): ≤0.005%

storage temp.

2-30°C

InChI

1S/Na.HO3P/c;1-4(2)3/h;(H,1,2,3)/q+1;/p-1

InChI key

AQMNWCRSESPIJM-UHFFFAOYSA-M

Application


  • Novel method for the preparation of controlled-release theophylline granules coated with a polyelectrolyte complex of sodium polyphosphate-chitosan.: This paper presents a novel approach to creating controlled-release theophylline granules using a coating made from a polyelectrolyte complex of sodium polyphosphate and chitosan. This method could significantly impact pharmaceutical formulations by improving drug release profiles and patient compliance (Kawashima et al., 1985).

Analysis Note

Assay (acidimetric, P₂O₅): ≥ 68 %
Identity: passes test
Chloride (Cl): ≤ 0.02 %
Heavy metals (as Pb): ≤ 0.005 %
Fe (Iron): ≤ 0.01 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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